Special Commentary on Maximum Acceptable Toxicant Concentration (MATC)

Primary tabs

BEMS reports,2018,4,2,37-38.
Published:March 2019
Type:News Letter
Author(s) affiliations:

K.S. Rao

Advinus Therapeutics Ltd, 21 and 22, Phase II, Peenya Industrial Area, Bengaluru – 560058, Karnataka, INDIA.


MATC is a value that is calculated through aquatic toxicity tests to help set water quality regulations for the protection of aquatic life. Using the results of a partial life-cycle chronic toxicity test, the MATC is reported as the geometric mean between the No Observed Effect Concentration (NOEC) and the Lowest Observed Effect Concentration (LOEC). The MATC is used to set regulatory standards for priority pollutants under the US federal Clean Water Act. Regulatory guidelines give two acceptable concentrations of pollutants to protect against effects: chronic or acute. MATC is a range of concentrations of a toxic substance in an environment that is between ‘No Observable Adverse Effect Level (NOAEL)’ and the ‘Lowest Observable Adverse Effect level (LOAEL)’. In other words, MATC is the highest concentration at which a pollutant can be present and not exert an adverse effect on the Biota, used to experimentally determine the toxicity of the chemical. Read more...